REJEON PCL Filler Allurar Anti-wrinkle dagawa da tabbatarwa
Farashin REJEON PCL
A cikin shekaru 20 da suka gabata, fahimtarmu game da ɗaya daga cikin wurare masu rikitarwa na jikin ɗan adam - fuska - ya inganta sosai, tare da sababbin tsarin jiki da yawa.
A lokaci guda, da yawa na marasa tiyata
hanyoyin sun zama samuwa don magani
alamun tsufa da maido da samari
bayyanar fuska. REJEON shine na farko, kuma
a halin yanzu kadai, collagen sti mulator wanda aka yi da polycaprolactone microspheres, wanda ke ba da gudummawa ga ingantaccen kayan haɓakawa. REJEON
Kaddarorin na musamman suna nufin zaɓi ne da ake so don kewayon hanyoyin nama mai laushi.
Takaitawa
Abubuwan da ke ciki na REJ EO N,
7 0% na tushen CMC mai ruwa
jigilar gelkuma30% PCL
abun da ke ciki,damar don
sakamako mai cika nan da nan
CMC ya haifar da shi, wanda ya biyo baya ta hanyar motsa jiki na kansa collagen (neocollagenesis).
An canza CMC 2 zuwa 3
watanni bayan allurakuma ana ci gaba da maye gurbinsa da na majiyyaci
collagen (mafi rinjaye nau'in I) wanda aka motsa ta
PCL microspheres. Hakanan microspheres na PCL suna da bioresorbable.
REJEON yana da halaye da yawa waɗanda suka sa ya zama zaɓi mai ban sha'awa a matsayin filler:
① Ƙwararren microspheres na polymer, a cikin kusan wata 1, da kuma haɗin haɗin gwiwar collagen yana hana ƙarin halayen kumburi daga faruwa13
Nau'in collagen mai ɗorewa a cikin rukunin da aka yi masa allura galibi shine '' balagagge '' collagen scafold na nau'in collagen I5
a) Rage nau'in collagen na III yana nufin babu wani ƙarin ƙarfafawa na amsawar kumburi
③An gama lalata abubuwan abubuwan REJEON ta hanyar hydrolysis, barin kawai ruwa da carbon dioxide.
④Saboda ƙarar ƙarshe a cikin yankin da ake bi da ita ya fi ƙarar Ellansé allura, babu buƙatar 'taɓawa' magani.
a) Ƙarshe na ƙarshe ya fi ƙarar da aka yi masa da kashi 20-30% saboda samuwar nau'in collagen I fibers11.
⑤ Samuwar nau'ikan REJEON guda biyu tare da tsawon lokaci na aiki yana nufin cewa tsawon tasirin jiyya na iya dacewa da na majiyyaci.
bukatun
a) Ana samun wannan ta hanyar canza tsayin sarƙoƙin PCL, ba da izini don tsinkaya, sarrafawa da daidaitacce bioresorption.
⑥ Dabarar jiyya iri ɗaya ce ba tare da la'akari da samfurin REJEON da aka zaɓa ba a) iri ɗaya:
● Rheological Properties
● Dabaru
● sirinji
● Allura/cannula
REJEON PCL Musamman abun da ke ciki
REJEON PCL ya ƙunshi na musamman, mai haƙƙin mallaka
hade da:
● 7 0% carboxymethyl cellulose (CMC) - tushen jigilar gel
● 3 0% polycaprolactone (PCL) microspheres (Hoto 1 .4) 3 , 4 , 5
Ana gudanar da microspheres PCL a ciki
dakatarwa iri ɗaya a cikin jigilar jigilar gel na tushen CMC. PCL da CMC duka suna da ingantaccen bayanin martabar haɓakar halittu.
REJEON PCL albarkatun kasa sun fito daga Gemany
PCL MICROSPHERES
PCL polyester ne na likitanci mara guba, wanda aka fara haɗa shi a farkon 1930s4, wato
m don amfani a cikin dermal fillers saboda sauƙi na bioresorption; a dabi'a ana sanya shi cikin ruwa zuwa carbon dioxide da ruwa a cikin jiki5.
Ana amfani da microspheres PCL a ciki
An tsara RE JEON don bayarwa
mafi kyawu a biocompatibility6 . Suna da fili mai santsi, a
siffar siffar zobe da girman girman
kusan 25-50 μm
PCL yana da kyakkyawan bayanin martaba na aminci3 kuma an yi amfani dashi a fagen ilimin halittu fiye da shekaru 70 don aikace-aikacen da yawa, daga sutures zuwa nama da maye gurbin gabobin ta hanyar buga 3D (Hoto 1.6)4. Hakanan ana amfani dashi a cikin alamar CE da Abincin Amurka da
Gudanar da Magunguna (FDA) - samfuran da aka yarda.
DUKIYAR CMC
CMC abu ne na halitta wanda aka samo daga cellulose; ba a haɗa shi ba, kuma ba mai guba ba ne. Sauran kaddarorinsa sun haɗa da (Hoto 1.7)4 :
● Sanannen kayan aikin magunguna ne
Yana da hygroscopic
FDA ta keɓe shi kamar yadda gabaɗaya ta amince da shi azaman lafiya (GRAS)
● Resorption yana faruwa a cikin watanni 2 - 3
Babban fa'idodin REJEON PCL Filler
REJEON PCL yana da microsphere na musamman kuma cikakke, tare da girman barbashi wanda ya dace da ka'idodin aminci na ƙasa da ƙasa da ƙasa mai santsi wanda zai iya ci gaba da haɓaka haɓakar collagen.
Ƙarfafa Collagen ta REJEON: Shaidar Kimiyya
REJEON ya kasance
gwada a cikin dabba
samfurin inda aka yi wa zomaye allura
ko da REJEON S
(PCL-1) ko REJEON M (PCL-2) don bincika neocollagenesis5.
Wata tara bayan allurar PCL-1,
neocollagenesis ya faru kuma PCL microspheres na PCL-1 sun kasance cikakke (Figure 1. 1 1) 5.
A halin yanzu, tare da PCL-2 a watanni 9,
akwai shaidar samuwar
rubuta I da nau'in III collagen a kusa
PCL microspheres. A cikin watanni 2 1 bayan allura, PCL-2 microspheres har yanzu suna nan a cikin ƙwayar allurar5.
A cikin binciken matukin jirgi na RE JEO N a cikin mutane, an shigar da marasa lafiya don karɓar Ellansé allurar ciki a cikin haikalin.
yanki9 . Binciken tarihi na nama da aka samu daga biopsies da aka bayyana
samuwar collagen a kusa da allurar PCL da aka yi (Hoto 1. 12) 9, yana goyan bayan irin wannan binciken da aka nuna a baya.
naman zomo5 .
REJEON tsarin aiki
REJEON yana da nau'ikan ayyuka daban-daban guda biyu (Hoto 1.9)1,4:
● Mataki na 1: Nan da nan bayan allura, sashin CMC yana ba da ƙarar ɗan lokaci,
wanda a hankali yana raguwa sama da watanni 2-3
● Mataki na 2: PCL microspheres induces
neocollagenesis na nau'ikan I da III collagen, tare da ƙarin nau'in collagen na ci gaba
A hankali tsarin yana ƙaruwa sama da watanni 1 - 3 da PCL microspheres
zama a cikin nau'in I collagen
zamba. Sakamakon ƙarar collagen
ya maye gurbin ƙarar ƙarar farko ta hanyar gel CMC
Ƙaƙƙarfan collagen wanda PCL ya motsa
microspheres na ci gaba bayan an sake dawo da su, yana haifar da ƙarar ƙarar ƙarar da aka gani tare da REJEON
REJEON PCL Filler yana da sakamako mai kyau
REJEON PCL Filler babban wakili ne mai dorewa mai dorewa wanda zai iya daidaita alamun da aka bari ta lokaci kuma ya dawo da kyan gani da ƙuruciya a fuska.
REJEON PCL FILLER BAYANIN MAGANAR CUSTOMER
Mun yi niyyar raba gwanintar mu da
sanin lokacin da yadda za a haɗa r ej eon a cikin aikin asibiti. Ina fatan zai amfanar da mai karatu kamar yadda ya yi mini aiki a cikin shekaru 10 da suka gabata: bayar da ingantattun jiyya tare da kyakkyawan sakamako da sakamako mai dorewa. RE JEON kayan aiki ne na asali a cikin aikina kuma ya sanya ni mafi kyawun allura! ”
Dr Francisco de Melo
Likitan Filastik, UAE
"RE JEON ya kasance abin da na fi so don maganin dermal
shekaru 7. Wannan labarin zai taimake ka ka koyi amfani da
RE JEON kuma za ku yi soyayya da shi. ”
Dr Shang-Li Lin
Likitan fata, Taiwan
“ Ingantaccen tsari da fata
ingancin da aka samo daga RE JOE N' s na musamman
neocollagenesis ba daidai ba. Babu shakka ɗayan kayan aikin mafi kyawun asibitoci waɗanda ke son ingantaccen inganci da aminci a cikin samfurin allura. REJ EO N yana da
iyawar samar da ɗagawa mai dorewa da ingantaccen tsarin fuska tare da zama ɗaya kawai. ”
Dr Ingrid Ló pez- Gehrke
Likitan fata, Mexico
"Na ji daɗin amfani da RE JEON saboda tasirin waƙar Vol umi mai ban mamaki. Wannan yana ba da damar ƙasa
samfurin da za a yi amfani da shi, kuma ta hanyar samar da nau'in collagen na ainihi, yana da ƙarfin gaske ga fata
sabuntawa. Yawancin marasa lafiya suna gaya mani: 'Wannan shine karo na farko
Ina da wani abu mai ɗorewa', ko 'Duba ingancin fata ta'. Tabbas filler na fi so. ”
Dokta Pierre Nicolau
Likitan Filastik, Spain
JININ MANYAN MILESTONES
Bayan bincike mai zurfi da haɓakawa, da kuma asibiti
gwaji, REJEON ya sami takardar shedar Tsarin Gudanar da Ingancin ISO 13485 a cikin
20081 (Hoto 1.2). A cikin 2009, alamar Amincewar Turai (CE) ta kasance
bayarwa, jagoranci
zuwa ga nasarar ƙaddamar da nasara
samfurin a cikin UK, Jamus da Spain. Sauran ƙaddamarwa sun biyo baya, tare da yin rijista fiye da 69
kasashe nan da shekarar 2018. Zuwa shekarar 2019, da
Shekaru 10 na rejeon, ƙari
An sayar da sirinji sama da miliyan 1
duniya. Amma labarin nasara bai tsaya a nan ba, tare da sabon rukunin masana'antu a Netherlands ya fara
samarwa a shekarar 2020
REJEON PCL Bayanin Samfura
1 ml/ guda
Karɓar marufi na musamman na OEM
